- 3 Seventeenth Street
- 1 Seventeenth Street
- 38 Seventeenth Street
- 1 Seventh Street
- 87 Seventh Street
- 27 Seventieth Street
- 1 Seventy-Eighth Street
- 2 Seventy-First Street
- 1 Sewall, Day & Co.
- 1 Seward's Laundry
- 6 Sewerage
- 7 Sewing
- 8 Sewing equipment & supplies
- 5 Sewing machine industry
- 7 Sewing machines
- 1 Seymour Street
- 1 Seymour, Horatio, 1810-1886
- 1 Seymour, Robert, 1798-1836
- 3 Shackles
- 1 Shadewall's Coverlet Manufactory
- 17 Shadows
- 1 Shadrach (Biblical figure)
- 1 Shaftesbury, Anthony Ashley Cooper, Earl of, 1801-1885
- 2 Shah Shuja
- 29 Shahnamah
- 1 Shahnameh
- 1 Shaker (Christian sect)
- 1 Shakespeare Bowling Saloon
- 1 Shakespeare Building
- 1 Shakespeare memorial
- 1 Shakespeare, William, 1564-1616
- 43 Shakespeare, William, 1564-1616.
- 1 Shaking hands
- 3 Shallcross' Mill
- 1 Shamrocks
- 1 Shanklin, England
- 2 Shantyville
- 12 Shape notes
- 1 Shapur I
- 1 Sharecroppers
