- 1 Schafter & Roberts, Furness, Brinley & Co.
- 1 Schantz, Horace W., 1875-19??
- 1 Scheaf of Wheat Tavern
- 1 Schenectady, New York
- 2 Schepper Bros. (cotton, woolen yarns)
- 2 Scheveningen, The Hague, Netherlands
- 1 Schilcher, Fred.
- 1 Schiller Park Brewery
- 1 Schisshytte-Molnebo Iron Works
- 1 Schlesinger, Sebastian Benzon
- 1 Schlieper & Baum
- 1 Schmidt & Gruninger
- 1 Schmidt, Henry
- 1 Schmidt, J. P. (Johann Philipp), 1779-1853
- 1 Schmidt's Paper Box Factory
- 1 Schmoele & Co. Hats (Firm)
- 1 Schoefield and Branson Woolen Mill
- 1 Schoen-Jackson Co.
- 1 Schoettle, F. Paper Box Factory
- 1 Schofield Mills
- 1 Schofield, Joseph Cotton & Woolen Waste
- 5 Scholars
- 1 Scholastica, Saint, 6th cent.
- 1 Schollenberger, W. & Sons Leather Manufactory
- 1 Schomacker Piano Co.
- 8 School children
- 18 School House Lane
- 2 School of Design
- 1 School of Industry
- 11 Schoolhouses
- 637 Schools
- 5 Schools (institutions)
- 17 Schooners
- 1 Schrack Paint Co.
- 1 Schroeder's Marble Yard
- 2 Schulkill Hose Company
- 1 Schull, D.J.-Coach Manufacturer
- 1 Schulz, Theodor, 1770-1850
- 1 Schumacher & Ettinger
- 1 Schumann's Tannery
