- 31 Skyscrapers
- 2 Skywalks
- 1 Slapstick comedies
- 2 Slate (rock)
- 1 Slate (roofing)
- 1 Slater's Mill
- 14 Slaughterhouses
- 5 Slaughtering
- 2 Slave trade
- 16 Slavery
- 3 Slaves (people)
- 2 Slavonia, Croatia
- 8 Sleds
- 1 Sleeper & Brother
- 7 Sleeping
- 1 Sleeve ruffs
- 10 Sleighs
- 1 Sliding
- 3 Sliding boards
- 1 Slingshots
- 1 Slippers
- 1 Sloan & Hutton, Architects
- 24 Sloan, Samuel, 1815-1884, Architect
- 1 Sloat Sewing Machine Factory
- 1 Slough, England
- 1 Slums
- 2 Small
- 1 Smedley, Frank E. (Frank Edward), 1818-1864
- 6 Smelters (metalworking plants)
- 1 Smith & Hodgson's Chemical Works
- 1 Smith and Lynch (firm)
- 1 Smith Bros.
- 1 Smith Day Nursery Drive
- 9 Smith Island, Pennsylvania
- 11 Smith Island, Pennsylvania
- 4 Smith, Albert Richard, 1816-1860
- 4 Smith, Alfred Al Emanuel, 1873-1944
- 6 Smith, Arthur W. W., 1825-1861
- 4 Smith, Charles Enterprise Oil Works
- 1 Smith, Clemens Lawrence, 1844-1909
